I agree about how much money it costs to develop and test a new drug, but what i absolutely despise is the re-patenting of the same drug with different functional groups which are biologically inert, or even increments of increase which are so small that several drugs trials are performed in parallel so that if one produces statistically significant, it is due to variation, as the other 19 are not significant.
This has been going on for decades, and it is disgusting as it often leads to a maintenence of drug price even after the original patent has expired, they produce what is medically speaking the same drug but marginally different (not more efficient), and stop other companies producing the drug at significantly reduced cost to the customers. This happens a lot in america, but worldwide and those who suffer are people who cannot afford the still expensive drugs.